publications from Studies supported by FHI Clinical

Title
Journal
Date
Indication
Final analysis of efficacy and safety of single-dose Ad26.COV2.S
New England Journal of Medicine
2022/03
COVID-19
Tafenoquine exposure assessment, safety, and relapse prevention efficacy in children with Plasmodium vivax malaria: open-label, single-arm, non-comparative, multicentre, pharmacokinetic bridging, phase 2 trial
The Lancet Child and Adolescent Health
2022/02
Malaria
Efficacy, safety and tolerability of pyronaridine-artesunate in asymptomatic malaria-infected individuals: a randomized controlled trial
Clinical Infectious Diseases
2022/01
Malaria
Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study
The Lancet Infectious Diseases
2022/01
Rotavirus gastroenteritis
A plain language summary of how well the single-dose Janssen vaccine works and how safe it is
Future Virology
2021/11
COVID-19
Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials
PLOS Pathogens
2021/11
HIV
Immunogenicity of alternative ten-valent pneumococcal conjugate vaccine schedules in infants in Ho Chi Minh City, Vietnam: results from a single-blind, parallel-group, open-label, randomised, controlled trial
The Lancet Infectious Diseases
2021/10
Pneumococcal pneumonia
Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-blind, randomised, placebo-controlled, phase 3 trial
The Lancet Respiratory Medicine
2021/10
COVID-19
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial
PLoS Medicine
2021/09
Nutrition
Performance analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial cohort
Critical Care Explorations
2021/07
COVID-19
Immunogenicity and safety of a novel ten-valent pneumococcal conjugate vaccine in healthy infants in The Gambia: a phase 3, randomised, double-blind, non-inferiority trial
The Lancet Infectious Diseases
2021/06
Pneumococcal pneumonia
Pyronaridine–artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study
PLoS Medicine
2021/06
Malaria
Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma
PLoS Neglected Tropical Diseases
2021/06
Schistosomiasis
Safety and efficacy of single-dose Ad26.COV2.S vaccine against COVID-19
New England Journal of Medicine
2021/06
COVID-19
Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam
Vaccine
2021/04
Pneumococcal pneumonia
Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial
The Lancet Respiratory Medicine
2021/04
Tuberculosis
PREVAIL IV: A randomized, double-blind, two-phase, phase 2 trial of remdesivir versus placebo for reduction of Ebola virus RNA in the semen of male survivors
Clinical Infectious Diseases
2021/03
Ebola
Hepatic safety of repeated treatment with pyronaridine‐artesunate versus artemether–lumefantrine in patients with uncomplicated malaria: a secondary analysis of the WANECAM 1 data from Bobo-Dioulasso, Burkina Faso
Malaria Journal
2021/01
Malaria
REGN-EB3: First Approval
Drugs
2021/01
Ebola
Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community
Scientific Reports
2021/01
Pneumonia
Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries
Trials
2021/01
Ebola
Economic evaluation protocol of a short, all-oral bedaquiline-containing regimen for the treatment of rifampicin-resistant tuberculosis from the STREAM trial
BMJ Open
2020/12
Tuberculosis
Ebola-negative neonates born to Ebola-infected mothers after monoclonal antibody therapy: a case series
Lancet Child and Adolescent Health
2020/12
Ebola
Challenges for drug repurposing in the COVID-19 pandemic era
Frontiers in Pharmacology
2020/11
COVID-19
DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: a randomized controlled, double-blind phase 2b trial
Vaccine
2020/10
Tuberculosis
Remdesivir for the treatment of Covid-19 — final report
New England Journal of Medicine
2020/10
COVID-19
Effect of Enhanced Adherence Package on Early ART Uptake Among HIV-Positive Pregnant Women in Zambia: An Individual Randomized Controlled Trial
AIDS and Behavior
2020/10
HIV
Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria
Pharmacogenetics and Genomics
2020/09
Malaria
The Equatoguinean Malaria Vaccine Initiative: from the launching of a clinical research platform to malaria elimination planning in central West Africa
American Journal of Tropical Medicine and Hygiene
2020/09
Malaria
Brief communication: immunogenicity of measles vaccine when co-administered with 10-valent pneumococcal conjugate vaccine
NPJ Vaccines
2020/08
Pneumonia
The potential of CBC-derived ratios (monocyte-to-lymphocyte, neutrophil-to-lymphocyte, and platelet-to-lymphocyte) to predict or diagnose incident TB infection in Tanzanian adolescents
BMC Infectious Diseases
2020/08
Tuberculosis
Respiratory syncytial virus vaccination during pregnancy and effects in infants
New England Journal of Medicine
2020/07
Respiratory syncytial virus
Safety and immunogenicity of a parenteral trivalent P2-VP8 subunit rotavirus vaccine: a multisite, randomised, double-blind, placebo-controlled trial
The Lancet Infectious Diseases
2020/07
Rotavirus gastroenteritis
Efficacy of a spatial repellent for control of malaria in Indonesia: a cluster-randomized controlled trial
American Journal of Tropical Medicine and Hygiene
2020/07
Malaria
Serostatus cutoff levels and fold increase to define seroresponse to recombinant vesicular stomatitis virus – Zaire Ebola virus envelope glycoprotein vaccine: An evidence-based analysis
Vaccine
2020/06
Ebola
Economic evaluation of short treatment for multidrug-resistant tuberculosis, Ethiopia and South Africa: the STREAM trial
Bulletin of the World Health Organization
2020/05
Tuberculosis
The China tuberculosis clinical trials consortium network: a model for international TB clinical trials capacity building
Infectious Diseases of Poverty
2020/05
Tuberculosis
Impact of the COVID-19 epidemic on a Pan-Asian academic oncology clinical trial
JCO Global Oncology
2020/04
Oncology
Effect of a chikungunya virus–like particle vaccine on safety and tolerability outcomes
JAMA
2020/04
Chikungunya
A phase 1b randomized study of the safety and immunological responses to vaccination with H4:IC31, H56:IC31, and BCG revaccination in Mycobacterium tuberculosis-uninfected adolescents in Cape Town, South Africa
eClinicalMedicine
2020/03
Tuberculosis
Pregnancy outcomes among women receiving rVSVΔ-ZEBOV-GP Ebola vaccine during the Sierra Leone Trial to Introduce a Vaccine against Ebola
Emerging Infectious Diseases
2020/03
Ebola
The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis
Parasites & Vectors
2020/03
Lymphatic filariasis
A Phase 2/3 double blinded, randomized, placebo-controlled study in healthy adult participants in Vietnam to examine the safety and immunogenicity of an inactivated whole virion, alum adjuvanted, A(H5N1) influenza vaccine (IVACFLU-A/H5N1)
Vaccine
2020/02
Avian influenza
Safety and immunogenicity of a novel 10-valent pneumococcal conjugate vaccine candidate in adults, toddlers, and infants in The Gambia-Results of a phase 1/2 randomized, double-blinded, controlled trial
Vaccine
2020/01
Pneumonia
A randomized, controlled trial of Ebola virus disease therapeutics
New England Journal of Medicine
2019/12
Ebola
Cytomegalovirus infection is a risk factor for tuberculosis disease in infants
JCI Insight
2019/12
Tuberculosis
Efficacy and safety of sodium zirconium cyclosilicate in patients with baseline serum potassium level ≥ 5.5 mmol/L: pooled analysis from two phase 3 trials
BMC Nephrology
2019/12
Cardiology
Portable infrared imaging for longitudinal limb volume monitoring in patients with lymphatic filariasis
PLoS Neglected Tropical Diseases
2019/10
Lymphatic filariasis
Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples
PLoS One
2019/08
Ebola
Final analyses of OPTiM: a randomized phase III trial of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in unresectable stage III-IV melanoma
Journal for the Immunotherapy of Cancer
2019/06
Oncology (Melanoma)
PREVAIL I cluster vaccination study with rVSVΔG-ZEBOV-GP as part of a public health response in Liberia
Journal of Infectious Diseases
2019/05
Ebola
Immunogenicity and reactogenicity of ten-valent versus 13-valent pneumococcal conjugate vaccines among infants in Ho Chi Minh City, Vietnam: a randomised controlled trial
The Lancet Infectious Diseases
2019/05
Pneumonia
A trial of a shorter regimen for rifampin-resistant tuberculosis
New England Journal of Medicine
2019/03
Tuberculosis
A longitudinal study of Ebola sequelae in Liberia
New England Journal of Medicine
2019/03
Ebola
Ebola virus disease-related stigma among survivors declined in Liberia over an 18-month, post-outbreak period: An observational cohort study
PLoS Neglected Tropical Diseases
2019/02
Ebola
Dose optimization of H56:IC31 vaccine for tuberculosis-endemic populations. a double-blind, placebo-controlled, dose-selection trial
American Journal of Respiratory and Critical Care Medicine
2019/01
Tuberculosis
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method
Scientific Reports
2019/01
Malaria
Single-dose tafenoquine to prevent relapse of Plasmodium vivax malaria
New England Journal of Medicine
2019/01
Malaria
Tafenoquine versus primaquine to prevent relapse of Plasmodium vivax malaria
New England Journal of Medicine
2019/01
Malaria
First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1
PLoS One
2018/11
HIV
Timing of rotavirus vaccine doses and severe rotavirus gastroenteritis among vaccinated infants in low- and middle-income countries
Epidemiology
2018/11
Rotavirus gastroenteritis
A randomized trial of a new triple drug treatment for lymphatic filariasis
New England Journal of Medicine
2018/11
Lymphatic filariasis
A review of strategies used to retain participants in clinical research during an infectious disease outbreak: The PREVAIL I Ebola vaccine trial experience
Contemporary Clinical Trials Communications
2018/09
Ebola
Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomised factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide
BMJ Open
2018/07
Malnutrition
Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19)
The Lancet
2018/07
HIV
Prevention of M. tuberculosis infection with H4:IC31 vaccine or BCG revaccination
New England Journal of Medicine
2018/07
Tuberculosis
Utilizing nurses to staff an Ebola vaccine clinical trial in Sierra Leone during the Ebola outbreak
Journal of Infectious Diseases
2018/06
Ebola
The Sierra Leone Trial to Introduce a Vaccine Against Ebola: An evaluation of rVSV∆G-ZEBOV-GP vaccine tolerability and safety during the West Africa Ebola outbreak
Journal of Infectious Diseases
2018/06
Ebola
Rapid establishment of a cold chain capacity of –60°C or colder for the STRIVE Ebola vaccine trial during the Ebola outbreak in Sierra Leone
Journal of Infectious Diseases
2018/06
Ebola
Participant retention in a randomized clinical trial in an outbreak setting: Lessons from the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE)
Journal of Infectious Diseases
2018/06
Ebola
Operationalizing international regulatory standards in a limited-resource setting during an epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE) experience
Journal of Infectious Diseases
2018/06
Ebola
Monitoring serious adverse events in the Sierra Leone Trial to Introduce a Vaccine Against Ebola
Journal of Infectious Diseases
2018/06
Ebola
Lessons learned in clinical trial communication during an Ebola outbreak: The implementation of STRIVE
Journal of Infectious Diseases
2018/06
Ebola
Implementing a multisite clinical trial in the midst of an Ebola outbreak: Lessons learned from the Sierra Leone Trial to Introduce a Vaccine Against Ebola
Journal of Infectious Diseases
2018/06
Ebola
Health conditions in an adult population in Sierra Leone: Data reported from the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE)
Journal of Infectious Diseases
2018/06
Ebola
Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial
BMJ Open
2018/06
Pneumonia
Clinical surveillance and evaluation of suspected Ebola cases in a vaccine trial during an Ebola epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola
Journal of Infectious Diseases
2018/06
Ebola
Use of the Filovirus Animal Non-Clinical Group (FANG) Ebola virus immuno-assay requires fewer study participants to power a study than the Alpha Diagnostic International assay
Journal of Virological Methods
2018/05
Ebola
Timing and predictors of severe rotavirus gastroenteritis among unvaccinated infants in low- and middle-income countries
Epidemiology and Infection
2018/04
Rotavirus gastroenteritis
Pyronaridine–artesunate or dihydroartemisinin–piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial
Lancet
2018/04
Malaria
Safety and immunogenicity of the novel tuberculosis vaccine ID93 + GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase 1 trial
The Lancet Respiratory Medicine
2018/04
Tuberculosis
Safety and immunogenicity of newborn MVA85A vaccination and selective, delayed Bacille Calmette-Guerin for infants of human immunodeficiency virus-infected mothers: a phase 2 randomized, controlled trial
Clinical Infectious Diseases
2018/02
Tuberculosis
Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study
Journal of Intensive Care
2018/02
Sepsis
Advancing global health through development and clinical trials partnerships: a randomized, placebo-controlled, double-blind assessment of safety, tolerability, and immunogenicity of PfSPZ vaccine for malaria in healthy Equatoguinean men
American Journal of Tropical Medicine and Hygiene
2018/01
Malaria
Use of a novel portable three-dimensional imaging system to measure limb volume and circumference in patients with filarial lymphedema
American Journal of Tropical Medicine and Hygiene
2017/12
Lymphatic filariasis
Phase 2 placebo-controlled trial of two vaccines to prevent Ebola in Liberia
New England Journal of Medicine
2017/10
Ebola
Cerebrospinal fluid examination in survivors of Ebola virus disease
JAMA Neurology
2017/09
Ebola
Durable response rate as an endpoint in cancer immunotherapy: insights from oncolytic virus clinical trials
Journal for the Immunotherapy of Cancer
2017/09
Oncology (melanoma)
Clinical development of a recombinant Ebola vaccine in the midst of an unprecedented epidemic
Vaccine
2017/08
Ebola
Conventional wisdom versus actual outcomes: challenges in the conduct of an Ebola vaccine trial in Liberia during the International Public Health Emergency
American Journal of Tropical Medicine and Hygiene
2017/07
Ebola
Abrogation of red blood cell G6PD enzyme activity through Heat treatment: development of survey material for the UK NEQAS G6PD scheme
International Journal of Laboratory Hemotology
2017/06
Malaria
Safety and immunogenicity of the recombinant Mycobacterium bovis BCG vaccine VPM1002 in HIV-unexposed newborn infants in South Africa
Clinical and Vaccine Immunology
2017/06
Tuberculosis
Establishment of a research pharmacy to support Ebola clinical research in Liberia
Science and Practice Advances in Pharmacy Practice
2017/04
Ebola
Causes and outcomes of sepsis in Southeast Asia: A multinational multicentre cross-sectional study
Lancet Global Health
2017/02
Sepsis
Assessment and optimization of the GeneXpert diagnostic platform for detection of Ebola virus RNA in seminal fluid
Journal of Infectious Diseases
2017/02
Ebola
Estimation of the in vivo MIC of cipargamin in uncomplicated Plasmodium falciparum malaria
Antimicrobial Agents and Chemotherapy
2017/01
Malaria
First-in-human evaluation of the safety and immunogenicity of an intranasally administered replication-competent Sendai virus-vectored HIV type 1 Gag vaccine: induction of potent T-cell or antibody responses in prime-boost regimens
Journal of Infectious Diseases
2017/01
HIV
H1:IC31 vaccination is safe and induces long-lived TNF-α+IL-2+CD4 T cell responses in M. tuberculosis infected and uninfected adolescents: A randomized trial
Vaccine
2017/01
Tuberculosis
Heterogeneity of rotavirus vaccine efficacy among infants in developing countries
Pediatric Infectious Disease Journal
2017/01
Rotavirus gastroenteritis
Beating the odds: successful establishment of a phase II/III clinical research trial in resource-poor Liberia during the largest-ever Ebola outbreak
Contemporary Clinical Trials Communications
2016/12
Ebola
Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the phase III OPTiM trial
OncoTargets and Therapy
2016/11
Oncology (melanoma)
A randomized, controlled trial of ZMapp for Ebola virus infection
New England Journal of Medicine
2016/10
Ebola
Antimalarial activity of KAF156 in falciparum and vivax malaria
New England Journal of Medicine
2016/09
Malaria
Ebola surveillance — Guinea, Liberia, and Sierra Leone
Morbidity and Mortality Weekly Report (MMWR)
2016/07
Ebola
Ebola virus persistence in semen of male survivors
Clinical Infectious Diseases
2016/06
Ebola
HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial
Retrovirology
2016/06
HIV
Assessing clinical research capacity in Vietnam: A framework for strengthening capability for clinical trials in developing countries
Public Health Reports
2016/05
Sepsis
Fostering collaboration on post-Ebola clinical research in Liberia
The Lancet Global Health
2016/04
Ebola
Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam
Journal of Virus Eradication
2016/04
HIV
Assessment of the safety and immunogenicity of 2 novel vaccine platforms for HIV-1 prevention: a randomized trial
Annals of Internal Medicine
2016/03
HIV
Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: Design, procedures, and challenges
Clinical Trials
2016/02
Ebola
Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial
Lancet Infectious Diseases
2016/02
Malaria
Factors associated with HIV RNA viral loads in ART-naïve patients: implications for treatment as prevention in concentrated epidemics
Journal of Virus Eradication
2016/01
HIV
Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial
Lancet Infectious Diseases
2016/01
Malaria
Population pharmacokinetics of pyronaridine in pediatric malaria patients
Antimicrobial Agents and Chemotherapy
2015/12
Malaria
Evaluation of Xpert® MTB/RIF assay in induced sputum and gastric lavage samples from young children with suspected tuberculosis from the MVA85A TB vaccine trial
PLOS One
2015/11
Tuberculosis
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma
Journal Of Clinical Oncology
2015/09
Oncology (melanoma)
TH17-mediated protection against pneumococcal carriage by a whole-cell vaccine is dependent on toll-like receptor 2 and surface lipoproteins
Clinical and Vaccine Immunology
2015/07
Pneumonia
The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial
Vaccine
2015/07
Tuberculosis
A phase I double blind, placebo-controlled, randomized study of the safety and immunogenicity of an adjuvanted HIV-1 Gag-Pol-Nef fusion protein and adenovirus 35 Gag-RT-Int-Nef vaccine in healthy HIV-uninfected African adults
PLoS One
2015/05
HIV
Multiple factors affect immunogenicity of DNA plasmid HIV vaccines in human clinical trials
Vaccine
2015/05
HIV
Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial
The Lancet Respiratory Medicine
2015/03
Tuberculosis
Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial
JAMA Network
2014/12
Cardiology
Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A
BMC Infectious Diseases
2014/12
Tuberculosis
The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses
Vaccine
2014/10
Tuberculosis
Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response
BMC Infectious Diseases
2014/06
Tuberculosis
Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study
The Lancet
2014/03
Malaria
Helicase-primase inhibitor pritelivir for HSV-2 infection
New England Journal of Medicine
2014/01
Genital herpes
A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients
Journal of Infectious Diseases
2013/05
Dengue
Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks
Journal of Antimicrobial Chemotherapy
2013/03
Influenza
Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
The Lancet
2013/02
Tuberculosis
Clinical validation of a point-of-care multiplexed in vitro immunoassay using monoclonal antibodies (the MSD Influenza Test) in four hospitals in Vietnam
Journal of Clinical Microbiology
2012/05
Influenza
Malnutrition levels among vaccinated and unvaccinated children between 2 and 3 years of age following enrollment in a randomized clinical trial with the pentavalent rotavirus vaccine (PRV) in Bangladesh
Vaccine
2012/04
Rotavirus gastroenteritis
A phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis–infected adults
American Journal of Respiratory and Critical Care Medicine
2012/01
Tuberculosis
The utility of Aspirin in Dukes C and High Risk Dukes B Colorectal cancer–the ASCOLT study: study protocol for a randomized controlled trial
Trials
2011/12
Oncology
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)
PLOS One
2011/08
HIV
Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants
Journal of Infectious Diseases
2011/06
Tuberculosis
Immunogenicity and safety of an investigational fully liquid hexavalent combination vaccine versus licensed combination vaccines at 6, 10, and 14 weeks of age in healthy South African infants
Pediatric Infectious Disease Journal
2011/04
Polyvalent vaccine
Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial
The Lancet
2010/08
Rotavirus gastroenteritis
Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial
The Lancet
2010/08
Rotavirus gastroenteritis
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial
Lancet
2010/04
Malaria
The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults
American Journal of Respiratory and Critical Care Medicine
2010/02
Tuberculosis
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
European Journal of Immunology
2009/12
Tuberculosis
Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa
Journal of Infectious Diseases
2008/08
Tuberculosis