Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial | The Lancet: Respiratory Medicine | | |
Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection | | | |
Evaluation of the protective efficacy of a spatial repellent to reduce malaria incidence in children in western Kenya compared to placebo: study protocol for a cluster-randomized double-blinded control trial (the AEGIS program) | | | |
Analysis of serious adverse events in a pediatric community-acquired pneumonia randomized clinical trial in Malawi | | | |
Final analysis of efficacy and safety of single-dose Ad26.COV2.S | New England Journal of Medicine | | |
Genome-wide pharmacogenetics of anti-drug antibody response to bococizumab highlights key residues in HLA DRB1 and DQB1 | | | |
Safety profile of bosutinib in Japanese versus non-Japanese patients with chronic myeloid leukemia: a pooled analysis | International Journal of Hematology | | |
Tafenoquine exposure assessment, safety, and relapse prevention efficacy in children with Plasmodium vivax malaria: open-label, single-arm, non-comparative, multicentre, pharmacokinetic bridging, phase 2 trial | The Lancet Child and Adolescent Health | | |
CAPRISA 018: a phase I/II clinical trial study protocol to assess the safety, acceptability, tolerability and pharmacokinetics of a sustained-release tenofovir alafenamide subdermal implant for HIV prevention in women | | | |
Chest radiography in children aged 2-59 months enrolled in the Innovative Treatments in Pneumonia (ITIP) project in Lilongwe Malawi: a secondary analysis | | | |
Efficacy, safety and tolerability of pyronaridine-artesunate in asymptomatic malaria-infected individuals: a randomized controlled trial | Clinical Infectious Diseases | | |
Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study | The Lancet Infectious Diseases | | Rotavirus gastroenteritis |
Efficacy and safety following bosutinib dose reduction in patients with Philadelphia chromosome‒positive leukemias | | | |
A plain language summary of how well the single-dose Janssen vaccine works and how safe it is | | | |
Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials | | | |
Efficacy and safety of palbociclib in patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer with preexisting conditions: A post hoc analysis of PALOMA-2 | | | |
Immunogenicity of alternative ten-valent pneumococcal conjugate vaccine schedules in infants in Ho Chi Minh City, Vietnam: results from a single-blind, parallel-group, open-label, randomised, controlled trial | The Lancet Infectious Diseases | | |
Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-blind, randomised, placebo-controlled, phase 3 trial | The Lancet Respiratory Medicine | | |
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial | | | |
Lowering cholesterol, blood pressure, or both to prevent cardiovascular events: results of 8.7 years of follow-up of Heart Outcomes Evaluation Prevention (HOPE)-3 study participants | | | |
A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19 | The Journal of Clinical Evaluation | | |
Efficacy and safety of bosutinib versus imatinib for newly diagnosed chronic myeloid leukemia in the Asian subpopulation of the phase 3 BFORE trial | International Journal of Hematology | | |
Evaluation of the association of polymorphisms with palbociclib-induced neutropenia: pharmacogenetic analysis of PALOMA-2/-3 | | | |
Genetic associations with weight gain among South Africans who initiated dolutegravir-containing and tenofovir-containing regimens | Journal of Acquired Immune Deficiency Syndrome | | |
Optimising pyrazinamide for the treatment of tuberculosis | European Respiratory Review | | |
Performance analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial cohort | Critical Care Explorations | | |
Immunogenicity and safety of a novel ten-valent pneumococcal conjugate vaccine in healthy infants in The Gambia: a phase 3, randomised, double-blind, non-inferiority trial | The Lancet Infectious Diseases | | |
Pyronaridine–artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study | | | |
Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma | PLoS Neglected Tropical Diseases | | |
Safety and efficacy of single-dose Ad26.COV2.S vaccine against COVID-19 | New England Journal of Medicine | | |
Antihypertensives and statin therapy for primary stroke prevention: A secondary analysis of the HOPE-3 trial | | | |
Long-term pooled safety analysis of palbociclib in combination with endocrine therapy for hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: updated analysis with up to 5 years of follow-up | | | |
Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam | | | |
Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial | The Lancet Respiratory Medicine | | |
Vadadustat in patients with anemia and non-dialysis-dependent CKD | New England Journal of Medicine | | |
PREVAIL IV: A randomized, double-blind, two-phase, phase 2 trial of remdesivir versus placebo for reduction of Ebola virus RNA in the semen of male survivors | Clinical Infectious Diseases | | |
Malawian children with fast-breathing pneumonia with and without comorbidities | | | |
Hepatic safety of repeated treatment with pyronaridine‐artesunate versus artemether–lumefantrine in patients with uncomplicated malaria: a secondary analysis of the WANECAM 1 data from Bobo-Dioulasso, Burkina Faso | | | |
Impact of dose reduction on efficacy: implications of exposure-response analysis of palbociclib | | | |
| | | |
Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community | | | |
Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries | | | |
Economic evaluation protocol of a short, all-oral bedaquiline-containing regimen for the treatment of rifampicin-resistant tuberculosis from the STREAM trial | | | |
Ebola-negative neonates born to Ebola-infected mothers after monoclonal antibody therapy: a case series | Lancet Child and Adolescent Health | | |
Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase | | | |
Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial | | | |
Challenges for drug repurposing in the COVID-19 pandemic era | Frontiers in Pharmacology | | |
Treatment effect of palbociclib plus endocrine therapy by prognostic and intrinsic subtype and biomarker analysis in patients with bone-only disease: a joint analysis of PALOMA-2 and PALOMA-3 clinical trials | Breast Cancer Research and Treatment | | |
DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: a randomized controlled, double-blind phase 2b trial | | | |
Dolutegravir with emtricitabine and tenofovir alafenamide or tenofovir disoproxil fumarate versus efavirenz, emtricitabine, and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection (ADVANCE): week 96 results from a randomised, phase 3, non-inferiority trial | | | |
Remdesivir for the treatment of Covid-19 — final report | New England Journal of Medicine | | |
Effect of Enhanced Adherence Package on Early ART Uptake Among HIV-Positive Pregnant Women in Zambia: An Individual Randomized Controlled Trial | | | |
Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria | Pharmacogenetics and Genomics | | |
The Equatoguinean Malaria Vaccine Initiative: from the launching of a clinical research platform to malaria elimination planning in central West Africa | American Journal of Tropical Medicine and Hygiene | | |
Brief communication: immunogenicity of measles vaccine when co-administered with 10-valent pneumococcal conjugate vaccine | | | |
The potential of CBC-derived ratios (monocyte-to-lymphocyte, neutrophil-to-lymphocyte, and platelet-to-lymphocyte) to predict or diagnose incident TB infection in Tanzanian adolescents | | | |
Amoxicillin for 3 or 5 days for chest-indrawing pneumonia in Malawian children | New England Journal of Medicine | | |
Respiratory syncytial virus vaccination during pregnancy and effects in infants | New England Journal of Medicine | | Respiratory syncytial virus |
Safety and immunogenicity of a parenteral trivalent P2-VP8 subunit rotavirus vaccine: a multisite, randomised, double-blind, placebo-controlled trial | The Lancet Infectious Diseases | | Rotavirus gastroenteritis |
Efficacy of a spatial repellent for control of malaria in Indonesia: a cluster-randomized controlled trial | American Journal of Tropical Medicine and Hygiene | | |
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial | | | |
Once-weekly rifapentine and isoniazid for tuberculosis prevention in patients with HIV taking dolutegravir-based antiretroviral therapy: a phase 1/2 trial | | | |
Serostatus cutoff levels and fold increase to define seroresponse to recombinant
vesicular stomatitis virus – Zaire Ebola virus envelope glycoprotein vaccine: An evidence-based analysis | | | |
Economic evaluation of short treatment for multidrug-resistant tuberculosis, Ethiopia and South Africa: the STREAM trial | Bulletin of the World Health Organization | | |
The China tuberculosis clinical trials consortium network: a model for international TB clinical trials capacity building | Infectious Diseases of Poverty | | |
Concordance of real-world versus conventional progression-free survival from a phase 3 trial of endocrine therapy as first-line treatment for metastatic breast cancer | | | |
Impact of the COVID-19 epidemic on a Pan-Asian academic oncology clinical trial | | | |
Effect of a chikungunya virus–like particle vaccine on safety and tolerability outcomes | | | |
Non-inferiority designs comparing placebo to a proven therapy for childhood pneumonia in low-resource settings | | | |
Progression-free survival outcome is independent of objective response in patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer treated with palbociclib plus letrozole compared with letrozole: analysis from PALOMA-2 | | | |
A phase 1b randomized study of the safety and immunological responses to vaccination with H4:IC31, H56:IC31, and BCG revaccination in Mycobacterium tuberculosis-uninfected adolescents in Cape Town, South Africa | | | |
Fourteen-day bactericidal activity, safety, and pharmacokinetics of linezolid in adults with drug-sensitive pulmonary tuberculosis | Antimicrobial Agents and Chemotherapy | | |
Hematologic adverse events following palbociclib dose reduction in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: pooled analysis from randomized phase 2 and 3 studies | | | |
Pregnancy outcomes among women receiving rVSVΔ-ZEBOV-GP Ebola vaccine during the Sierra Leone Trial to Introduce a Vaccine against Ebola | Emerging Infectious Diseases | | |
Safety, tolerability, pharmacokinetics, and antimalarial activity of the novel plasmodium phosphatidylinositol 4-kinase inhibitor MMV390048 in healthy volunteers | Antimicrobial Agents and Chemotherapy | | |
The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis | | | |
A Phase 2/3 double blinded, randomized, placebo-controlled study in healthy adult participants in Vietnam to examine the safety and immunogenicity of an inactivated whole virion, alum adjuvanted, A(H5N1) influenza vaccine (IVACFLU-A/H5N1) | | | |
Safety and immunogenicity of a novel 10-valent pneumococcal conjugate vaccine candidate in adults, toddlers, and infants in The Gambia-Results of a phase 1/2 randomized, double-blinded, controlled trial | | | |
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events | | | |
A randomized, controlled trial of Ebola virus disease therapeutics | New England Journal of Medicine | | |
Cytomegalovirus infection is a risk factor for tuberculosis disease in infants | | | |
Efficacy and safety of sodium zirconium cyclosilicate in patients with baseline serum potassium level ≥ 5.5 mmol/L: pooled analysis from two phase 3 trials | | | |
Palbociclib with letrozole in postmenopausal women with ER+/HER2- advanced breast cancer: hematologic safety analysis of the randomized PALOMA-2 trial | | | |
Portable infrared imaging for longitudinal limb volume monitoring in patients with lymphatic filariasis | PLoS Neglected Tropical Diseases | | |
Analysis of serious adverse events in a paediatric fast breathing pneumonia clinical trial in Malawi | BMJ Open Respiratory Research | | |
Neutropenia management with palbociclib in Japanese patients with advanced breast cancer | Breast Cancer Research and Treatment | | |
Dolutegravir plus two different prodrugs of tenofovir to treat HIV | New England Journal of Medicine | | |
Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples | | | |
Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line | | | |
The cost implication of primary prevention in the HOPE 3 trial | | | |
Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): a phase 3 randomised controlled trial | The Lancet: Gastroenterology and Hepatology | | |
Final analyses of OPTiM: a randomized phase III trial of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in unresectable stage III-IV melanoma | Journal for the Immunotherapy of Cancer | | |
Patient-reported outcomes in the phase 3 BFORE trial of bosutinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia | Journal of Cancer Research and Clinical Oncology | | |
PREVAIL I cluster vaccination study with rVSVΔG-ZEBOV-GP as part of a public health response in Liberia | Journal of Infectious Diseases | | |
Immunogenicity and reactogenicity of ten-valent versus 13-valent pneumococcal conjugate vaccines among infants in Ho Chi Minh City, Vietnam: a randomised controlled trial | The Lancet Infectious Diseases | | |
Palbociclib plus letrozole as first-line therapy in postmenopausal Asian women with metastatic breast cancer: results from the phase III, randomized PALOMA-2 study | Journal of Global Oncology | | |
Statin use in primary prevention: A simple trial-based approach compared with guideline-recommended risk algorithms for selection of eligible patients | Canadian Journal of Cardiology | | |
Long-term pooled safety analysis of palbociclib in combination with endocrine therapy for HR+/HER2- advanced breast cancer | Journal of the National Cancer Institute | | |
Palbociclib plus letrozole as first-line therapy in estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer with extended follow-up | Breast Cancer Research and Treatment | | |
A longitudinal study of Ebola sequelae in Liberia | New England Journal of Medicine | | |
A trial of a shorter regimen for rifampin-resistant tuberculosis | New England Journal of Medicine | | |
Effects of blood pressure and lipid lowering on cognition: Results from the HOPE-3 study | | | |
Palbociclib in combination with letrozole in patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-2 subgroup analysis of Japanese patients | International Journal of Global Oncology | | |
Ebola virus disease-related stigma among survivors declined in Liberia over an 18-month, post-outbreak period: An observational cohort study | PLoS Neglected Tropical Diseases | | |
Dose optimization of H56:IC31 vaccine for tuberculosis-endemic populations. a double-blind, placebo-controlled, dose-selection trial | American Journal of Respiratory and Critical Care Medicine | | |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method | | | |
Placebo vs amoxicillin for nonsevere fast-breathing pneumonia in Malawian children aged 2 to 59 months: a double-blind, randomized clinical noninferiority trial | | | |
Single-dose tafenoquine to prevent relapse of Plasmodium vivax malaria | New England Journal of Medicine | | |
Tafenoquine versus primaquine to prevent relapse of Plasmodium vivax malaria | New England Journal of Medicine | | |
A randomized trial of a new triple drug treatment for lymphatic filariasis | New England Journal of Medicine | | |
First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1 | | | |
Tenofovir 1% vaginal gel for prevention of HIV-1 infection in women in South Africa (FACTS-001): a phase 3, randomised, double-blind, placebo-controlled trial | The Lancet: Infectious Diseases | | |
Timing of rotavirus vaccine doses and severe rotavirus gastroenteritis among vaccinated infants in low- and middle-income countries | | | Rotavirus gastroenteritis |
Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial | | | |
A review of strategies used to retain participants in clinical research during an infectious disease outbreak: The PREVAIL I Ebola vaccine trial experience | Contemporary Clinical Trials Communications | | |
Methods for conducting a double-blind randomized controlled clinical trial of three days versus five days of amoxicillin dispersible tablets for chest indrawing childhood pneumonia among children two to 59 months of age in Lilongwe, Malawi: a study protocol | | | |
Palbociclib plus endocrine therapy in older women with HR+/HER2- advanced breast cancer: a pooled analysis of randomised PALOMA clinical studies | European Journal of Cancer | | |
Safety and efficacy of second-line bosutinib for chronic phase chronic myeloid leukemia over a five-year period: final results of a phase I/II study | Journal of Clinical Lipidology | | |
Cardiovascular event reduction with PCSK9 inhibition among 1578 patients with familial hypercholesterolemia: Results from the SPIRE randomized trials of bococizumab | Journal of Clinical Lipidology | | |
Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT): a protocol for a randomised factorial, double-blind, placebo-controlled trial of azithromycin, nitazoxanide and nicotinamide | | | |
Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19) | | | |
Prevention of M. tuberculosis infection with H4:IC31 vaccine or BCG revaccination | New England Journal of Medicine | | |
Residual inflammatory risk on treatment with PCSK9 inhibition and statin therapy | | | |
Utilizing nurses to staff an Ebola vaccine clinical trial in Sierra Leone during the Ebola outbreak | Journal of Infectious Diseases | | |
The Sierra Leone Trial to Introduce a Vaccine Against Ebola: An evaluation of rVSV∆G-ZEBOV-GP vaccine tolerability and safety during the West Africa Ebola outbreak | Journal of Infectious Diseases | | |
Rapid establishment of a cold chain capacity of –60°C or colder for the STRIVE Ebola vaccine trial during the Ebola outbreak in Sierra Leone | Journal of Infectious Diseases | | |
Participant retention in a randomized clinical trial in an outbreak setting: Lessons from the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE) | Journal of Infectious Diseases | | |
Operationalizing international regulatory standards in a limited-resource setting during an epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE) experience | Journal of Infectious Diseases | | |
Monitoring serious adverse events in the Sierra Leone Trial to Introduce a Vaccine Against Ebola | Journal of Infectious Diseases | | |
Lessons learned in clinical trial communication during an Ebola outbreak: The implementation of STRIVE | Journal of Infectious Diseases | | |
Implementing a multisite clinical trial in the midst of an Ebola outbreak: Lessons learned from the Sierra Leone Trial to Introduce a Vaccine Against Ebola | Journal of Infectious Diseases | | |
Health conditions in an adult population in Sierra Leone: Data reported from the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE) | Journal of Infectious Diseases | | |
Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial | | | |
Clinical surveillance and evaluation of suspected Ebola cases in a vaccine trial during an Ebola epidemic: The Sierra Leone Trial to Introduce a Vaccine Against Ebola | Journal of Infectious Diseases | | |
Use of the Filovirus Animal Non-Clinical Group (FANG) Ebola virus immuno-assay requires fewer study participants to power a study than the Alpha Diagnostic International assay | Journal of Virological Methods | | |
Impact of palbociclib plus letrozole on patient-reported health-related quality of life: results from the PALOMA-2 trial | | | |
Pyronaridine–artesunate or dihydroartemisinin–piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial | | | |
Safety and immunogenicity of the novel tuberculosis vaccine ID93 + GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase 1 trial | The Lancet Respiratory Medicine | | |
Timing and predictors of severe rotavirus gastroenteritis among unvaccinated infants in low- and middle-income countries | Epidemiology and Infection | | Rotavirus gastroenteritis |
Clinical considerations of the role of palbociclib in the management of advanced breast cancer patients with and without visceral metastases | | | |
Long-term patient-reported outcomes from an open-label safety and efficacy study of bosutinib in Philadelphia chromosome-positive chronic myeloid leukemia patients resistant or intolerant to prior therapy | | | |
Safety and immunogenicity of newborn MVA85A vaccination and selective, delayed Bacille Calmette-Guerin for infants of human immunodeficiency virus-infected mothers: a phase 2 randomized, controlled trial | Clinical Infectious Diseases | | |
Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study | Journal of Intensive Care | | |
Advancing global health through development and clinical trials partnerships: a randomized, placebo-controlled, double-blind assessment of safety, tolerability, and immunogenicity of PfSPZ vaccine for malaria in healthy Equatoguinean men | American Journal of Tropical Medicine and Hygiene | | |
Bosutinib versus imatinib for newly diagnosed chronic myeloid leukemia: results from the randomized BFORE trial | Journal of Clinical Oncology | | |
Comprehensive analysis of survival outcomes in non-clear cell renal cell carcinoma patients treated in clinical trials | Clinical Genitourinary Cancer | | |
Use of a novel portable three-dimensional imaging system to measure limb volume and circumference in patients with filarial lymphedema | American Journal of Tropical Medicine and Hygiene | | |
Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial | | | |
Phase 2 placebo-controlled trial of two vaccines to prevent Ebola in Liberia | New England Journal of Medicine | | |
Cerebrospinal fluid examination in survivors of Ebola virus disease | | | |
Durable response rate as an endpoint in cancer immunotherapy: insights from oncolytic virus clinical trials | Journal for the Immunotherapy of Cancer | | |
Clinical development of a recombinant Ebola vaccine in the midst of an unprecedented epidemic | | | |
Conventional wisdom versus actual outcomes: challenges in the conduct of an Ebola vaccine trial in Liberia during the International Public Health Emergency | American Journal of Tropical Medicine and Hygiene | | |
Abrogation of red blood cell G6PD enzyme activity through Heat treatment: development of survey material for the UK NEQAS G6PD scheme | International Journal of Laboratory Hemotology | | |
Safety and immunogenicity of the recombinant Mycobacterium bovis BCG vaccine VPM1002 in HIV-unexposed newborn infants in South Africa | Clinical and Vaccine Immunology | | |
Safety and immunogenicity of adenovirus 35 tuberculosis vaccine candidate in adults with active or previous tuberculosis. A randomized trial | American Journal of Respiratory and Critical Care Medicine | | |
Cardiovascular efficacy and safety of bococizumab in high-risk patients | New England Journal of Medicine | | |
Establishment of a research pharmacy to support Ebola clinical research in Liberia | Science and Practice Advances in Pharmacy Practice | | |
Causes and outcomes of sepsis in Southeast Asia: A multinational multicentre cross-sectional study | | | |
Assessment and optimization of the GeneXpert diagnostic platform for detection of Ebola virus RNA in seminal fluid | Journal of Infectious Diseases | | |
Estimation of the in vivo MIC of cipargamin in uncomplicated Plasmodium falciparum malaria | Antimicrobial Agents and Chemotherapy | | |
First-in-human evaluation of the safety and immunogenicity of an intranasally administered replication-competent Sendai virus-vectored HIV type 1 Gag vaccine: induction of potent T-cell or antibody responses in prime-boost regimens | Journal of Infectious Diseases | | |
H1:IC31 vaccination is safe and induces long-lived TNF-α+IL-2+CD4 T cell responses in M. tuberculosis infected and uninfected adolescents: A randomized trial | | | |
Heterogeneity of rotavirus vaccine efficacy among infants in developing countries | Pediatric Infectious Disease Journal | | Rotavirus gastroenteritis |
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial | The Lancet: Infectious Diseases | | |
Beating the odds: successful establishment of a phase II/III clinical research trial in resource-poor Liberia during the largest-ever Ebola outbreak | Contemporary Clinical Trials Communications | | |
Early tumour shrinkage: a tool for the detection of early clinical activity in metastatic renal cell carcinoma | | | Metastatic renal cell carcinoma |
Long-term bosutinib for chronic phase chronic myeloid leukemia after failure of imatinib plus dasatinib and/or nilotinib | American Journal of Hematology | | |
Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the phase III OPTiM trial | | | |
Palbociclib and letrozole in advanced breast cancer | New England Journal of Medicine | | |
A randomized, controlled trial of ZMapp for Ebola virus infection | New England Journal of Medicine | | |
Antimalarial activity of KAF156 in falciparum and vivax malaria | New England Journal of Medicine | | |
Health-related quality of life during bosutinib (SKI-606) therapy in patients with advanced chronic myeloid leukemia after imatinib failure | Current Medical Research and Opinion | | |
Ebola surveillance — Guinea, Liberia, and Sierra Leone | Morbidity and Mortality Weekly Report (MMWR) | | |
Ebola virus persistence in semen of male survivors | Clinical Infectious Diseases | | |
HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial | | | |
Assessing clinical research capacity in Vietnam: A framework for strengthening capability for clinical trials in developing countries | | | |
Blood-pressure lowering in intermediate-risk persons without cardiovascular disease | New England Journal of Medicine | | |
Blood-pressure and cholesterol lowering in persons without cardiovascular disease | New England Journal of Medicine | | |
Cholesterol lowering in intermediate-risk persons without cardiovascular disease | New England Journal of Medicine | | |
Repeated cycles of recombinant human interleukin 7 in HIV-infected patients with low CD4 T-cell reconstitution on antiretroviral therapy: results of 2 phase II multicenter studies | Clinical Infectious Behaviors | | |
Fostering collaboration on post-Ebola clinical research in Liberia | | | |
Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam | Journal of Virus Eradication | | |
Assessment of the safety and immunogenicity of 2 novel vaccine platforms for HIV-1 prevention: a randomized trial | Annals of Internal Medicine | | |
Novel approaches in primary cardiovascular disease prevention: The HOPE-3 trial rationale, design, and participants’ baseline characteristics | Canadian Journal of Cardiology | | |
Short-course treatment for multidrug-resistant tuberculosis: the STREAM trials | European Respiratory Review | | |
Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: Design, procedures, and challenges | | | |
Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial | Lancet Infectious Diseases | | |
Factors associated with HIV RNA viral loads in ART-naïve patients: implications for treatment as prevention in concentrated epidemics | Journal of Virus Eradication | | |
Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial | Lancet Infectious Diseases | | |
Factors influencing long-term efficacy and tolerability of bosutinib in chronic phase chronic myeloid leukaemia resistant or intolerant to imatinib | British Journal of Hematology | | |
Population pharmacokinetics of pyronaridine in pediatric malaria patients | Antimicrobial Agents and Chemotherapy | | |
Evaluation of Xpert® MTB/RIF assay in induced sputum and gastric lavage samples from young children with suspected tuberculosis from the MVA85A TB vaccine trial | | | |
Icatibant for multiple hereditary angioedema attacks across the controlled and open-label extension phases of FAST-3 | International Archives of Allergy and Immunology | | |
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma | Journal Of Clinical Oncology | | |
TH17-mediated protection against pneumococcal carriage by a whole-cell vaccine is dependent on toll-like receptor 2 and surface lipoproteins | Clinical and Vaccine Immunology | | |
The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial | | | |
A phase I double blind, placebo-controlled, randomized study of the safety and immunogenicity of an adjuvanted HIV-1 Gag-Pol-Nef fusion protein and adenovirus 35 Gag-RT-Int-Nef vaccine in healthy HIV-uninfected African adults | | | |
Multiple factors affect immunogenicity of DNA plasmid HIV vaccines in human clinical trials | | | |
Recombinant human-C1 inhibitor is effective and safe for repeat hereditary angioedema attacks | The Journal of Allergy and Clinical Immunology | | |
The safety and immunogenicity of an adenovirus type 35-vectored TB vaccine in HIV-infected, BCG-vaccinated adults with CD4(+) T cell counts >350 cells/mm(3) | | | |
Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial | The Lancet Respiratory Medicine | | |
Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial | | | |
Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A | | | |
Safety of bosutinib versus imatinib in the phase 3 BELA trial in newly diagnosed chronic phase chronic myeloid leukemia | American Journal of Hematology | | |
The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses | | | |
Safety of bosutinib versus imatinib in the phase 3 BELA trial in newly diagnosed chronic phase chronic myeloid leukemia | Allergy and Asthma Proceedings | | |
Bosutinib efficacy and safety in chronic phase chronic myeloid leukemia after imatinib resistance or intolerance: Minimum 24-month follow-up | American Journal of Hematology | | |
Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response | | | |
Population pharmacokinetic and pharmacodynamic analysis of bosutinib | Drug Metabolism and Pharmacokinetics | | Philadelphia chromosome–positive leukemia. |
Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial | Journal of Clinical Oncology | | Metastatic renal cell carcinoma |
Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study | | | |
Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors | | | |
Helicase-primase inhibitor pritelivir for HSV-2 infection | New England Journal of Medicine | | |
A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients | Journal of Infectious Diseases | | |
Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks | Journal of Antimicrobial Chemotherapy | | |
Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial | | | |
Health-related quality of life in chronic myeloid leukemia | | | |
Clinical efficacy of icatibant in the treatment of acute hereditary angioedema during the FAST-3 trial | Expert Review of Clinical Immunology | | |
Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial | Journal of Clinical Oncology | | |
Retigabine as adjunctive therapy in adults with partial-onset seizures: integrated analysis of three pivotal controlled trials | | | |
Clinical validation of a point-of-care multiplexed in vitro immunoassay using monoclonal antibodies (the MSD Influenza Test) in four hospitals in Vietnam | Journal of Clinical Microbiology | | |
Bosutinib is active in chronic phase chronic myeloid leukemia after imatinib and dasatinib and/or nilotinib therapy failure | | | |
Health-related quality of life of bosutinib (SKI-606) in imatinib-resistant or imatinib-intolerant chronic phase chronic myeloid leukemia | | | |
Malnutrition levels among vaccinated and unvaccinated children between 2 and 3 years of age following enrollment in a randomized clinical trial with the pentavalent rotavirus vaccine (PRV) in Bangladesh | | | Rotavirus gastroenteritis |
A phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis–infected adults | American Journal of Respiratory and Critical Care Medicine | | |
Randomized placebo-controlled trial of the bradykinin B₂ receptor antagonist icatibant for the treatment of acute attacks of hereditary angioedema: the FAST-3 trial | Annals of Asthma, Allergy and Immunology | | |
The utility of aspirin in Dukes C and High Risk Dukes B colorectal cancer–the ASCOLT study: study protocol for a randomized controlled trial | | | |
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib | | | |
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204) | | | |
Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants | Journal of Infectious Diseases | | |
Immunogenicity and safety of an investigational fully liquid hexavalent combination vaccine versus licensed combination vaccines at 6, 10, and 14 weeks of age in healthy South African infants | Pediatric Infectious Disease Journal | | |
Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial | | | Rotavirus gastroenteritis |
Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial | | | Rotavirus gastroenteritis |
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial | | | |
The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults | American Journal of Respiratory and Critical Care Medicine | | |
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells | European Journal of Immunology | | |
No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes | | | |
Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa | Journal of Infectious Diseases | | |
