Our capabilities and experience
Read more about how we help manage complex clinical research across many therapeutic areas worldwide.
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Lassa Fever Fact Sheet
Lassa fever is a type of hemorrhagic fever caused by the Lassa virus and is mainly transmitted by rodents. The virus was first detected in 1969 in the town of Lassa, in Borno State, Nigeria; hence, its name. Lassa is endemic to West Africa, specifically Nigeria, Liberia, Sierra Leone and Guinea. A significant number of individuals infected by the Lassa virus (~80%) do not appear to develop symptoms. The case fatality rate (CFR) has been reported to be upwards of 70%
Providing Site Monitoring and Management Expertise in Malaria Vaccine Trials in Equatorial Guinea
Data monitoring strategies implemented by our bilingual CRA helped eliminate the backlog to ensure timely database lock in a phase 2 trial for Sanaria’s innovative PfSPZ Vaccine for malaria in Equatorial Guinea, an area with limited prior research experience.
Research Capacity Brochure
Collaborative relationships ensure site sustainability. Keeping a site functional, even in slow times, preserves investment in human and equipment resources and ensures the site is ready to conduct quality research as soon as there is a need.
Cryptosporidiosis Fact Sheet
Cryptosporidium infection (cryptosporidiosis) is a diarrheal disease caused by tiny, one-celled Cryptosporidium parasites representing at least 15 genotypically and phenotypically diverse species. When these parasites enter the body, they travel to the distal small intestine and burrow into the intestinal walls. After 1-2 weeks, they are shed and excreted in feces. Infection can also occur in the respiratory tract.
Sickle Cell Fact Sheet
Sickle cell disease (SCD) is an inherited disorder of the red blood cells (RBCs). Sickle cell anemia is the most common type of SCD. RBCs carry oxygen throughout the body via hemoglobin. With SCD, defective hemoglobin replaces normal hemoglobin. Over time, this causes many RBCs to become rigid and sickle-shaped and die earlier than normal RBCs, leading to a constant shortage.
Chagas Disease Fact Sheet
Chagas disease (aka American trypanosomiasis) is a tropical parasitic disease caused by the protozoan parasite Trypanosoma cruzi that is found mostly in triatomine insects (aka “kissing bugs”) and in the Americas. Infection is life-long, with symptoms ranging from fever and headaches to enlarged internal organs.
Phase II/IIb Trial of a Zika Vaccine Spanning Nine Countries
In a study conducted at 17 sites spanning nine countries in a Zika endemic region of the Americas and Caribbean, timely staffing of contract research associates (CRAs) was enabled by the project team’s network of bilingual resources and knowledge of local hiring practices.
Clinical Research Training to Support Capacity Building in Liberia
To equip Liberia with the ability to respond to ongoing health issues and potential outbreaks, a US government contract provided funding to train local leaders in Liberia’s clinical research infrastructure network.
The training aimed to build a solid foundation to conduct international quality clinical research.
Our Clinical Trial Experience With Chikungunya Virus
CHIKV outbreaks have occurred in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans. It was found for the first time in the Americas on islands in the Caribbean in 2013 and has spread throughout most of the Americas. It has since been identified in over 60 countries in Asia, Africa, Europe and the Americas. No commercially available vaccine to prevent or medicine to treat CHIKV infection is currently available.
Building Capacity for Tuberculosis Research in China: The China TB Clinical Trials Consortium (CTCTC)
To help address the high global TB incidence and related death rate, the China TB Clinical Trials Consortium (CTCTC) was established by government and industry partners to help build clinical research capacity in China, which has a particularly high tuberculosis incidence.
