Sickle Cell Fact Sheet
Sickle cell disease (SCD) is an inherited disorder of the red blood cells (RBCs). Sickle cell anemia is the most common type of SCD. RBCs carry oxygen throughout the body via hemoglobin. With SCD, defective hemoglobin replaces normal hemoglobin. Over time, this causes many RBCs to become rigid and sickle-shaped and die earlier than normal RBCs, leading to a constant shortage.